IGF-II is regulated by microRNA-125b in skeletal myogenesis.

Ge Y, Sun Y, Chen J. J Cell Biol. 2011; 192(1):69-81. Learn more

A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy.

Goodman CA, Miu MH, Frey JW, Mabrey DM, Lincoln HC, Ge Y, Chen J, Hornberger TA. Mol. Biol. Cell 2010; 21(18):3258-68. Learn more

Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis.

Sun Y*, Ge Y*, Drnevich J, Zhao Y, Band M, Chen J. J Cell Biol. 2010; 189(7):1157-69. *Contributed equally. Learn more

Rheb and Raptor negatively regulate myogenesis through suppression of IRS1.

Ge Y, Yoon M, Chen J. J Biol Chem 2011; 286(41):35675-82. Learn more

mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms.

Ge Y, Wu AL, Warnes C, Liu J, Zhang C, Kawasome H, Terada N, Boppart MD, Schoenherr CJ, Chen J. Am J Physiol Cell Physiol 2009; 297(6):C1434-44. Learn more